Copyright 2012 Andrew Dobson
Read the latest “So, You’re A Cartoonist” at the following [link]
You can work on any sized paper with pretty much any tool you want as long as the end result is how you intended it. But if you're going into print, it's important to take into consideration how the end result will be presented before you begin working.
These are a variety of different sizes and formats for my comics and how they're affected by reduction, either for print or internet posting. The large comic pages are all 1:1 in relationship to each other so you can see the various sizes I work in. The smaller pages are the sizes they're shrunk down to in relation to their actual size. I hope that's not too confusing for people.
I didn't post any measurements for the bleed and gutter areas because that can change with the printing. It's important to know before you start working on a print job, what size you'll be working in and what your bleed area measurements are.